SpellsCurse
Sectumsempra
Sectumsempra is a curse written in the Half-Blood Prince’s textbook, labeled for enemies. It slashes the target as if by an invisible blade. Harry casts it at Draco Malfoy in a bathroom duel without knowing the effect. Snape arrives and counters the bleeding. The curse is Snape’s invention from his own school years.

First mention
Harry Potter and the Half-Blood PrinceChapter: Sectumsempra
Harry uses the curse on Malfoy beside the vanishing cabinet. He had already read the word in the Prince’s copy of Advanced Potion-Making.